Eric David Cassmann

DVM, PhD, Diplomate ACVP*
Associate Professor
5152940876
Patterson Hall
Education & Certifications  
  • Diplomate, American College of Veterinary Pathologists, 2021
  • PhD, Veterinary Pathology, Iowa State University College of Veterinary Medicine, 2019
  • DVM, Iowa State University College of Veterinary Medicine, 2013
  • BA, Biology and Spanish, Wartburg College, 2008 
  • Veterinary Medical License: Iowa (2015-present), New Mexico (2013-2015)
Teaching  
  • V Pth 342 -- Anatomic Pathology I (Dual-listed with 542.)
  • V Pth 456 -- Necropsy Laboratory Practicum
  • V Pth 604 -- Pathology Case Seminar
  • V Pth 571 -- Systemic Pathology II
  • V Pth 679 -- Histopathology of Laboratory Animals
Research Focus & Interests  
  • Neurodegenerative disease
  • Pathogenesis, detection, and control of prion diseases
  • Chronic Enteropathies
  • Diagnostic and Comparative Pathology
Honors & Awards  

2019 Research Excellence Award, Graduate College, Iowa State University

2018 Lora and Russ Talbot Graduate Fellowship in Veterinary Medicine

2018 Charles Louis Davis DVM Foundation, Student Scholarship Award

2017 Gamma Sigma Delta, Honor Society of Agriculture

2013 Robert Carithers Award for Excellence in Clinics, ISU CVM

2012 Janice M. Clark Memorial Scholarship, ISU CVM

2011 First Place Honors, ISU CVM Summer Scholars Research Symposium

2010 Comparative Gastroenterology Society Student Scholar Research Grant

2004 Board of Regents Merit Scholarship, Wartburg College: 4 years 

Leadership/Committees/Council  

Member, Ad-hoc committee for NADC Core Facility Research Services: Flow cytometry, genomics, and microscopy. Oct 2023 – present.

ARS Representative, Subject Matter Expert, Department of Interior–Department of Agriculture Joint CWD Task Force, 2022 – present.

Subject Matter Expert, ARS National Programs Croudsourcing Initiative. Detect to Protect Challenge: A Live Animal Test for CWD. 2020 – 2022.

Member, North American Interdisciplinary Chronic Wasting Disease Research Consortium – Multistate Research Project - National Information Management and Support System (NIMSS), 2022 – present.

Memberships  
  • American College of Veterinary Pathologists, 2021 – present
  • C.L Davis and S.W Thompson DVM Foundation (veterinary pathology), 2019 – present
  • Iowa Veterinary Medical Association, 2024 – present
  • American Veterinary Medical Association, 2011 – 2019; 2024 – present 
Selected Publications  

Google Scholar: https://scholar.google.com/citations?user=c1L0ljcAAAAJ&hl=en

Brown, Q., Nicholson, E., Wang, C., Greenlee, J., Seger, H., Veneziano, S., and Cassmann, E., Temporal serum neurofilament light chain concentrations in sheep inoculated with the agent of classical scrapie. PLoS One, 2024. 19(2): p. e0299038.

Cassmann, E., Frese, A.J., Becker, K.A., and Greenlee, J.J., Short incubation periods of atypical H-type BSE in cattle with EK211 and KK211 prion protein genotypes after intracranial inoculation. Front Vet Sci, 2023. 10: p. 1301998.

Cassmann, E., Frese, A.J., Moore, S.J., and Greenlee, J.J., Transmission of Raccoon-Passaged Chronic Wasting Disease Agent to White-Tailed Deer. Viruses, 2022. 14(7): p. 1578.

Cassmann, E., Brown, Q.L., Frese, A.J., Lambert, Z., Greenlee, M.H.W., and Greenlee, J.J., Effect of inoculation with prion dilutions within the dynamic range of ELISA absorbance on prion incubation period. Vet Res Commun, 2022.

Cassmann, E., Moore, S.J., and Greenlee, J.J., Experimental Oronasal Transmission of Chronic Wasting Disease Agent from White-Tailed Deer to Suffolk Sheep. Emerg Infect Dis, 2021. 27(12): p. 3156-3158.

Cassmann, E., Mammadova, N., Moore, S.J., Benestad, S., and Greenlee, J.J., Transmission of the atypical/Nor98 scrapie agent to Suffolk sheep with VRQ/ARQ, ARQ/ARQ, and ARQ/ARR genotypes. PLoS One, 2021. 16(2): p. e0246503.

Cassmann, E., Frese, R.D., and Greenlee, J.J., Second passage of chronic wasting disease of mule deer to sheep by intracranial inoculation compared to classical scrapie. J Vet Diagn Invest, 2021. 33(4): p. 711-720.

Mammadova, N., Cassmann, E., Moore, S.J., Nicholson, E.M., and Greenlee, J.J., Experimental inoculation of CD11c(+) B1 lymphocytes, CD68(+) macrophages, or platelet-rich plasma from scrapie-infected sheep into susceptible sheep results in variable infectivity. Access Microbiol, 2020. 2(9): p. acmi000155.

Cassmann, E., Mammadova, N., and Greenlee, J.J., Autoclave treatment of the classical scrapie agent US No. 13-7 and experimental inoculation to susceptible VRQ/ARQ sheep via the oral route results in decreased transmission efficiency. PLoS One, 2020. 15(12): p. e0243009.

Cassmann, E. and Greenlee, J.J., Pathogenesis, detection, and control of scrapie in sheep. Am J Vet Res, 2020. 81(7): p. 600-614.

Cassmann, E., Moore, S.J., Kokemuller, R., Balkema-Buschmann, A., Groschup, M., Nicholson, E., and Greenlee, J., Bovine adapted transmissible mink encephalopathy is similar to L-BSE after passage through sheep with the VRQ/VRQ genotype but not VRQ/ARQ. BMC Vet Res, 2020. 16(1): p. 383.

Householder, H.M., Cassmann, E., White, R., Fales-Williams, A., Viall, A.K., and Zaffarano, B.A., Paraplegia in a Domestic Ferret (Mustela Putorius Furo) Secondary to Metastatic Adrenocortical Carcinoma with Myxoid Differentiation. J Exot Pet Med, 2019. 29: p. 63-69.

Cassmann, E., Moore, S.J., Smith, J.D., and Greenlee, J.J., Sheep Are Susceptible to the Bovine Adapted Transmissible Mink Encephalopathy Agent by Intracranial Inoculation and Have Evidence of Infectivity in Lymphoid Tissues. Front Vet Sci, 2019. 6: p. 430.

Cassmann, E., Moore, S.J., Smith, J.D., and Greenlee, J.J., Sheep With the Homozygous Lysine-171 Prion Protein Genotype Are Resistant to Classical Scrapie After Experimental Oronasal Inoculation. Vet Pathol, 2019. 56(3): p. 409-417.

Cassmann, E., Zaffarano, B., Chen, Q., Li, G., and Haynes, J., Novel siadenovirus infection in a cockatiel with chronic liver disease. Virus Res, 2019. 263: p. 164-168.

Cassmann, E., White, R., Atherly, T., Wang, C., Sun, Y., Khoda, S., Mosher, C., Ackermann, M., and Jergens, A., Alterations of the Ileal and Colonic Mucosal Microbiota in Canine Chronic Enteropathies. PLoS One, 2016. 11(2): p. e0147321.